Jeffrey Klein MD

dr-jeffrey-kleinDr Jeffrey Klein is a dermatologic surgeon practicing in San Juan Capistrano and Newport Beach in Orange County, California. Dr. Klein is listed a Diplomat for the American Board of Dermatology, the American Board of Internal Medicine, and the American Board of Cosmetic Surgery. In addition to Dr. Klein has completed a National Institute of Health Research Fellowship in Clinical Pharmacology, as well as advanced degreesin mathematics and biostatistics.

As a result of his scientific training, he was able to invent the technique for tumescent local anesthesia and tumescent liposuction totally by local anesthesia. Dr. Klein first described the tumescent technique for liposuction at a scientific meeting in 1986 and published his result in the Journal of the American Academy of Cosmetic Surgery in 1987. Prior to 1986, all liposuction surgeries were done under general anesthesia, were associated with significant surgical blood loss and prolonged post-operative recovery of two or more weeks.

The advent of tumescent liposuction permitted liposuction to be done totally by local anesthesia with virtually no blood loss. Within a few years tumescent liposuction became the worldwide standard of care. If you go to Google and search for “Jeffrey Klein Liposuction” you will encounter more than 10,000 listings. More than 800 surgeons from around the world have traveled to San Juan Capistrano to attend Dr. Klein’s tumescent liposuction course known as Liposuction 101 (see www.liposuction101.com). In addition, Dr. Klein continues to be active in research and teaching at the University of California, Irvine and Riverside campuses.

Safety and patient comfort are Dr. Klein’s highest priority. The potential dangers and risks of liposuction are associated with general anesthesia, excessively large volumes of liposuction done on a single day, and combining liposuction with other unrelated procedures. Dr. Klein’s tumescent liposuction avoids all these risks factors. Dr. Klein’s patients are all fully conscious. There is no general anesthesia associated post-operative nausea and vomiting. Patients typically return to work in one to two days and need only wear postoperative elastic support garments for one to five days after surgery. Only acetaminophen (Tylenol®) is used for post-operative analgesia.

Today tumescent liposuction continues to be the world’s safest and most comfortable form of liposuction with the quickest recovery and best cosmetic results. Safety is Dr. Klein top priority. Experience has shown that Dr. Klein’s tumescent liposuction is safer than laser liposuction and ultrasound assisted liposuction (UAL).

 

Dr. Klein's Curriculum Vitae

Jeffrey Klein M.D. – Curriculum Vitae

Name:
Jeffrey Alan Klein, M.D.
Office Address:
30280 Rancho Viejo Road
San Juan Capistrano, CA 92675
Office Telephone: (949) 248-1632
FAX: (949) 248-9339
E-mail: jeffkleinmd@yahoo.com
Birth Date & Place: August 13, 1944. Los Angeles,California.
Citizenship: USA
Languages: English, Spanish, French
Wife: Kathleen Hutton-Klein, M.D.

ACADEMIC APPOINTMENTS:
Clinical Professor, Dermatology, University of California, Irvine
Adjunct Professor Statistics, University of California, Riverside

EDUCATION

School Degree Specialty Dates
University of California, Riverside BA Mathematics 1962-67
Universite de Paris   Mathematics 1967-68
University of California, San Diego MA Mathematics 1968-71
University of California, San Francisco MD Medicine 1972-76
University of California, Berkeley MPH Biostatistics 1971-72
University of California, Berkeley   Epidemiologys 1976-77
University of California, Los Angeles   Internal Medicine Resident 1977-80
University of London, Institute of Dermatology Dermatology   Mar-Apr 1980
All India Institute of Medical Sciences, New Delhi Dermatology   May-Jun 1980
University of California, San Francisco Clinical Pharmacology NIH Fellowship 1980-81
University of California, Irvine Pharmacology NIH Fellowship, Clinical 1980-81
University of California, Irvine Dermatology Resident   1981-84

 

Diplomat

American Board of Internal Medicine 1980
American Board of Dermatology 1984
American Board of Cosmetic Surgery 1989
Other Certifications Advanced Cardiac Life Support, Advanced Trauma Life Support
Present Activity Private Practice: Dermatology, Dermatologic Surgery, and Cosmetic Surgery.
Academic Appointments Associate Clinical Professor, Dermatology, University of California, Irvine 1985-Present
Previous Employment California Emergency Physicians, Inc., Emergency Room Physician 1979-1985

 

Professional Societies

  • American Academy of Dermatology
  • American Society for Mohs Surgery
  • American Society for Dermatologic Surgery
  • Dermatology Foundation
  • American Society of Anesthesiologists
  • California Society of Anesthesiologists
  • International Anesthesiology Research Society
  • Orange County Medical Association (OCMA)
  • California Medical Association
  • American Medical Association
  • Indian Association of Dermatologists Venereologists Leprologists AM/US/216/07)

 

Honors
American Society for Dermatologic Surgery President’s Award, 2004
Outstanding & Unique Contributions to Dermatologic Surgery and The American Society for Dermatologic Surgery.”

Leadership In Professional Societies

  • Founding Secretary: American Society for Mohs Surgery, 1994
  • President – Orange County Society for Dermatology, 2003-2004
  • Chairman (elect), Department of Dermatology, Hoag Hospital, Newport Beach, CA

 

Advisory Committee
The Dean’s Advisory Committee, College of Natural and Agricultural Sciences, University of California, Riverside. 2005 to 2012
University of California, Riverside Foundation, Board of Trustees 2012 to present

Recent Invited-Guest Lectureships

2004 British Association of Aesthetic Plastic Surgeons Chester, England
2005 Brazilian Society for Dermatologic Surgery Manaus, Brazil
2006 California Congress of Dermatology and Dermatologic Surgery San Diego, CA
2006 Italian Society for Aesthetic Surgery Rome
2006 Mass General Hospital, Wellman Institute, Laser Medicine Boston, MA
2008 Brazilian Society for Dermatologic Surgery Campo do Jordão, Brazil
2015 The ASDS Leadership in Innovation Lectureship Chicago, IL
2016 The AAD Eugene J. Van Scott Award for Innovative Therapy of the Skin and Phillip Frost Leadership Lecture Washington, DC

 

Commercial Interests Related to Medicine & Dermatologic Surgery

HK Surgical, Inc Surgical Supplies for Tumescent Anesthesia & Liposuction www.hksurgical.com
Liposuction.com Liposuction Information, Cost, Pictures and Surgeons Directory www.liposuction.com
Liposuction 101 – Liposuction Training Course Hands-On Liposuction Teaching Course (27 Hours CME) www.liposuction101.com
Newport Beach Liposuction Surgery KleinLipo Liposuction Surgery in Newport Beach www.kleinlipo.com

 

National Television Interviews

  • 20/20 (ABC) 1995
  • Larry King Live 1995

 

Scientific Publication

  1. Klein, JA. Optimal Statistical Techniques in Estimating Patient Compliance. Preventive Med, 1979.
  2. Klein JA, Cole G, Barr RJ, Bartlow G, Fulwider C. Paraffinoma of the Scalp, Arch Derm 121:382-385,1985.
  3. Klein JA, Barr RJ. Verrucous Hemangioma, J Pediat Derm, 2:191-193,1985.
  4. McCullough JL, Peckham P, Klein J, Weinstein GD, Jenkins JJ. Regulation of epidermal proliferation in mouse epidermis by combination of difluoromethyl ornithine (DFMO) and Methylglyoxal Bis(guanylhydrazone) (MGBG), J Invest Derm 85:518-521,1985.
  5. Klein JA, McCullough JL, Weinstein GD. Topical tritiated thymidine for epidermal growth fraction determination. J Invest Derm 86:406-409,1986.
  6. Klein JA, Barr RA. Diffuse lipomatosis and tuberous sclerosis. Arch Derm 122:1298-1302,1986.
  7. Klein JA. The tumescent technique for liposuction surgery. J Am Acad Cosmetic Surg 4:263-267,1987.
  8. Klein JA. Anesthesia for liposuction in dermatologic surgery. J Derm Surg Oncol 14:1124-1132,1988.
  9. Stewart JH, Cole GW, Klein JA. Neutralized lidocaine with epinephrine for local anesthesia. J Dermatol Surg Oncol 15:1081-1083,1989.
  10. Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35 mg/kg for liposuction. J Derm Surg Oncol 16:248-263,1990.
  11. Klein JA, Barr RJ. Bannayan-Zonana Syndrome Associated with Lymphangiomyomatous lesions. J Pediat Dermatol 7:48-53, 1990.
  12. Klein JA. The Tumescent Technique: Anesthesia and Modified Liposuction Technique. Dermatol Clinics 8:425-437,1990.
  13. Stewart JH, Chen SE, Cole GW, Klein JA. Neutralized lidocaine with epinephrine for local anesthesia, II. J Dermatol Surg Oncol 16:842-845,1990.
  14. Klein JA, Anesthesia for dermatologic cosmetic surgery. Coleman WP III, Hanke CW, Alt TH, Asken S, editors, Cosmetic Surgery of the Skin: Principles and Techniques. Philadelphia, B. C. Decker Inc. 1991, pp 39-45.
  15. Coleman WP III, Klein JA. Use of the tumescent technique for scalp surgery, dermabrasion, and soft tissue reconstruction. J Dermatol Surg Oncol 18:130,1992.
  16. Klein JA, Soins post-operatoires apres liposculpture utilisant la technique tumescente (Postoperative Care Following Liposuction by the Tumescent Technique), La Revue de Chirurgie Esthetique de Langue Francaise 17:5-8,1992.
  17. Klein JA. Tumescent technique for local anesthesia improves safety in large volume liposuction. Plast Reconstr Surg 92:1085-1098,1993.
  18. Klein JA. Reply: Ethics of promoting patient safety and comity among surgical specialties. [letter] Plast Reconstr Surg 95:603-604,1995.
  19. Klein JA. Establishing a Dermatologic Surgicenter, Elson M, editor, Evaluation and Treatment of the Aging Face. Springer-Verlag, publishers, New York 1995, pp 255-260.
  20. Klein JA, Liposuction. Moy R, Lask G, editors, Principles and Techniques of Cutaneous Surgery. Mc Graw-Hill, New York, 1996, pp 529-542.
  21. Klein JA, Tumescent liposuction and improved postoperative care using Tumescent Liposuction GarmentsT. Dermatol Clinics, 13:329-338, April 1995.
  22. Klein JA, Tumescent Technique Chronicles: Local Anesthesia, Liposuction, and Beyond. Dermatologic Surg. 21:449-457, 1995.
  23. Klein JA, Epitomes, Dermatology: Tumescent technique for local anesthesia. West J Med 124) Klein JA. Tumescent liposuction with local anesthesia. Principles and Techniques of Cutaneous Surgery. Lask GP, Moy RL editors. McGraw-Hill, New York, 1996. pp 529-542.
  24. Klein JA, Anesthesia for dermatologic cosmetic surgery. Coleman WP III, Hanke CW, Alt TH, Asken S, editors, Cosmetic Surgery of the Skin: Principles and Techniques. 2nd Edition. Philadelphia, B. C. Decker Inc., 1997
  25. Klein JA. Two Standards of Care for Tumescent Liposuction. Derm Surg J 24:1194-1195,1997
  26. Klein JA, Kassardjian N. Lidocaine Toxicity with Tumescent Liposuction, a case report of probable drug interactions. Derm Surg J 24:1169-1174,1997
  27. Klein JA, Tumescent Liposuction, Chapter 9, in Dzubow LM, editor, Cosmetic Dermatologic Surgery, Lippincott-Raven, Philadelphia, 1998,p163-169.
  28. Klein AW, Narins RS, Klein JA. Tumescent Liposuction. Fitzpatrick’s Dermatology in General Medicine, 5th edition, McGraw Hill, New York, 1999, pp2967-2969.
  29. Klein, JA. Intravenous fluids and bupivacaine are contraindicated in tumescent liposuction (letter), Plastic Reconstr Surg 102:2516-2518,1998.
  30. Klein JA. Anesthetic formulations of tumescent solutions. Dermatologic Clinics, 17:751-759,1999.
  31. Klein JA. Post-tumescent liposuction care: open drainage and bimodal compression. Dermatologic Clinics, 17:881-889,1999.
  32. Klein JA. Commentary: Fulton J. Modified Tumescent Liposuction. Dermatol Surg 25:764-766,1999.
  33. Klein JA. Discussion: Perry AW, Petti C, Rankin M. Lidocaine is not necessary in liposuction. Plast Reconstr Surg. 1999 Nov;104: discussion 1903-6
  34. Klein JA. Antibacterial effects of tumescent lidocaine. Plast Reconstr Surg. 1999 Nov;104:1934-6.
  35. Klein JA, Tumescent Technique: Tumescent Anesthesia & Microcannular Liposuction. Mosby, St. Louis, approx 500 pages. March, 2000.
  36. Klein JA. Pharmacology of Tumescent Liposuction. Ch 21. pp 443-445. In Cosmetic Surgery: An Interdisciplinary Approach, Narins RS editor, Marcel Dekker, New York, 2001.
  37. Klein JA Liposuction Using Dilute Local Anesthesia: Counterpoint. Dermatol Surg 29:1146-7, 2003.
  38. Klein JA, Is Tumescent Liposuction Safe?, Baran R, Maibach HI, Editors, Textbook of Cosmetic Surgery, 3rd ed. 2005, Chapter 64, pages 621-628, Taylor&Francis Publishers, London&New York (ISBN 1-84184-311-3)
  39. Kucera IJ, Lambert TJ, Klein JA, Watkins RG, Hoover JM, Kaye AD. Liposuction: contemporary issues for the anesthesiologist. J Clin Anesth. 18:379-87, 2006.
  40. Wanner M, Mihm MC, Jr, Farinelli WA, Doukas A, Zurakowski D, Piris A, Avram MM, Klein JA, Anderson RR. Use of Photodynamic Therapy and Sterile Water to Target Adipose Tissue. Dermatol Surg. 2015;41:803-11.
  41. Klein JA, Jeske DR. Estimated maximum safe dosage of tumescent lidocaine. Anesth Analg 2015, in press.
  42. Klein JA, Langman LJ. Tumescent Infiltration Drug Delivery: Pharmacokinetics of Subcutaneous Antibiotics for Prevention of Surgical Site Infection and Systemic Inflammation. Submitted to Anesth Analg 2015.
  43. Klein JA, Zand AR, Klein LEW, Klein PA, vanZandt J: invivoPFT: digital photographic analysis measurement of bleeding volume during a Ivy Bleeding Time test (ready for submission).

 

Current Research: Principal Investigator for Clinical Trials Registered on ClinicalTrials.Gov

  • NCT00977028 TLA Peak: Maximum Safe Dosage of Tumescent Lidocaine Without Liposuction
  • NCT01046981 TAD: Controlled Randomized Clinical Trial of Tumescent Cefazolin for Surgical Site Infection Prophylaxis
  • Paired Comparison Multi-Center Study of Open-Drainage vs. Close-Drainage Post-liposuction Care
  • Double-Blind Controlled Randomized Clinical Trial of Laser Liposuction
  • NCT01047722 BVT: ASA Bleeding Area test: A Double-Blind Crossover Randomized Clinical Trial of Aspirin Effect and Resistance
  • NCT01463280 BA-LidoLipo Tumescent Lidocaine Effects on Platelet Function Following Liposuction Surgical Trauma: A Prospective Controlled Dosage – Response Phase I Clinical Trial
  • NCT02503904 TISSITS Tumescent Infiltration of Antibiotics for Surgical Site Infection, Thrombosis and Sepsis Prophylaxis: A Multicenter Open Label Randomized Clinical Trial
  • Pending TIA4PHN Tumescent Infiltration Acyclovir for Post Herpetic Neuralgia Prophylaxis: A Multicenter Open Label Randomized Clinical Trial

 

United States Patents  (www.uspto.gov)

U.S. PAT. NO. Title
5,052,999 Liposuction method and apparatus
5,682,607 Skin appliqué to provide protection from ultraviolet light
D387,167 Liposuction patient positioning support (Design Patent)
5,817,050 Liposuction cannula
5,950,238 Post-liposuction breast compression garment and method for edema reduction
5,817,050 Liposuction cannula
6,032,669 Positioning pillow for approximating anatomic position in lateral decubitus position
6,162,960 Compression sponge for wound care
6,676,677 Liposuction cannula with abrading apertures
6,849,775 Method of forming absorbent pad using precut overlay
7,364,545 Method of measuring bleeding volume (2008)
7,572,613 Drug delivery system for accelerated subcutaneous absorption (2009)
7,914,504 Infiltration Cannula (March 29, 2011)
8,118,572 Peristaltic pump tubing with stopper and cooperative roller assembly housing having no moving parts (Feb 21, 2012)
8,923,477 B2 Fiducial System for Mammography (Aug 20, 2013)
8,957060 B2 Tumescent Antibiotic Solution (Feb. 17, 2015)

US 2012/0322783 A1 Patent Application Publication: Tumescent Antibiotic Solution (Dec 20, 2012)

NCT00977028 1 TLA Peak Tumescent Lidocaine Maximum Safe mg/kg Dosage
NCT01046981 2 TAD Tumescent Antibiotic Delivery: Pharmacokinetic Evidence For Improved Surgical Site Infection Prevention
NCT01047722 3 BVT-ASA In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction